What is Metatrol® – is it the same product as AvéULTRA?

When you are searching for where to buy your fermented wheat germ extract, it’s helpful to compare some of the popular brands to determine which one is the best for you. Metatrol contains the bioactive fraction from AvéULTRA; non-active fractions, including gliadin and gluten, are filtered out.

Research shows that fermented wheat germ extract (FWGE) provides health benefits by supporting regulation of both cellular metabolism and immune function.* FWGE consists of tens of thousands of molecules. Research by American BioSciences and academic research collaborators show that fewer than 100 molecules account for the 100% of the biological activity of FWGE, and technology was patented that concentrates this “bioactive fraction” into a substance called FWGE-SC™. Studies show that 41 mg of FWGE-SC, the amount found in two Metatrol capsules.

l capsules has the same biological activity as both 5,500 mg of FWGE, the amount found in one packet of AvéULTRA and 17,000 mg of spray-dried FWGE, the amount found in one packet of original Avé. (Fig. 1)


Why change the name to Metatrol?

The Metatrol name results from combining syllables from the words “metabolic” and “control”, which we hope will emphasize the primary benefit of this dietary supplement; the support of healthy cellular metabolic regulation that drives healthy gene expression.*

In healthy cells, metabolism involves the conversion of glucose with oxygen into a molecule called “ATP”, which fuels the function of healthy cells. Medical researchers have long known that stress and injury can alter cellular metabolism, in some cases stimulating non-oxidative metabolism and inhibiting oxidative metabolism. These cells no longer function in a healthy manner, and they disturb the normal function and metabolism of neighboring cells. Research shows that FWGE and FWGE-SC help support healthy oxidative metabolism, and inhibit non-oxidative metabolism that characterizes abnormal cells, restoring healthy cell function.*

Will I receive the same benefits from Metatrol as I did from AvéULTRA?

Yes, research shows that Metatrol provides the same health benefits as AvéULTRA, but it is much easier to take – just two capsules per day! No need to mix your fermented wheat germ extract suppliment with water or juice, and gluten and gliadin have been removed from Metatrol so that people with gluten allergies can take it without worries.

Are there any side effects from Metatrol?

Research shows that AvéULTRA FWGE is non-toxic. Only a small percent of users report stomach upset or change in stool, which could be caused by gluten and gliadin. Some AvéULTRA users complain about the taste, and difficulty mixing with water or juice. With new Metatrol fermented wheat germ extract, we expect even fewer user complaints. Gluten and gliadin are removed from FWGE, and the daily dose is just two capsules per day, so there’s nothing to mix and virtually no taste.

How can Fermented WHEAT Germ Extract be gluten-free?

Patent pending technology concentrates all the bioactive molecules in FWGE and filters out gluten and non-active molecules. Original Avé® and AvéULTRA had 665.5 mg of gluten per serving, while Metatrol contains only a trace of gluten, less than 20 ppm or 0.005 mg per capsule, and meets the Food and Drug Administration (FDA) definition of “gluten-free”.  This can provide you with the benefits of wheat germ nutrition without any of the side effects.

How many Metatrol capsules should I take?

When switching from AvéULTRA to Metatrol, substitute two Metatrol capsules for one packet of AvéULTRA.

Research shows that two Metatrol capsules, containing 41 mg of FWGE-SC, is bioequivalent to one packet of AvéULTRA, containing 5,500 mg of FWGE freeze-dried extract. We encourage everyone with serious health issues to consult with a physician for personal guidance. For adults weighing less than 200 lbs, the usage recommendation is to take two capsules per day, together at once or in divided doses. For people weighing over 200 lbs, four capsules per day are recommended. Consult with a health care practitioner for usage recommendations for children. Do not take when pregnant or nursing. Do not take if you are on immunosuppressive medication related to an organ transplant.

When should I take Metatrol?

AvéULTRA usage instructions suggested taking it one hour before or after meals, and two hours before or after any drugs or other dietary supplements.

Metatrol contains the “bioactive fraction” of AvéULTRA, consisting of fewer than 100 molecules with very low molecular weights, and are not degraded by active digestion, so you can take Metatrol before, during, or after meals. There has been no research showing that other dietary supplements will interfere with Metatrol, or that Metatrol interferes with any other dietary supplements, so you can take Metatrol whenever it is convenient.

When taking any prescription medication, review the “FDA package insert”, available with every drug for warnings and contraindications and consult with your doctors or with pharmacists.

Will Metatrol be more expensive than AvéULTRA?

No, Metatrol is the same price as AvéULTRA, despite the increased cost of manufacturing

Unlike AvéULTRA, which needs to be shipped on ice in climates where the temperature is above 80°F, Metatrol is stable at up to 122F, so it can be shipped by regular mail and without ice in areas where the outside temperature is under 100°F, so many customers will save money on shipping as well.

If I prefer, can I still get AvéULTRA?

Yes, AvéULTRA is still available, but we expect most people to switch to Metatrol.

Metatrol: the FWGE for everyone. Everything you want and need in FWGE, nothing you don’t!